| Cat. No. |
Product Name |
Information |
| PC-61133 |
RUC-4
|
Zalunfiban (RUC-4) is a potent, selective, non-RGD-mimetic αIIbβ3 integrin receptor antagonist with IC50 of 45 nM, with no activity on αVβ3 receptors. |
| PC-60253 |
Leukadherin 1
CD11b agonist
|
Leukadherin 1 (LA1) is a small molecule allosteric agonist of integrin CD11b/CD18 (CR3), increases CD11b/CD18-dependent cell adhesion to fibrinogen (EC50=4 uM). |
| PC-70068 |
Cyclo(RGDyK)
αvβ3 integrin inhibitor
|
Cyclo(RGDyK) (Cyclic Arg-Gly-Asp-D-Tyr-Lys) is a cyclic derivative of RGD, potent, selective αVβ3 integrin inhibitor with IC50 of 20 nM. |
| PC-70014 |
BIO-7662
Integrin α4β1 inhibitor
|
BIO-7662 (BIO7662) is a potent, highly selective α4β1 integrin antagonist with Kd of <10 pM. |
| PC-60070 |
GSK-3008348 hydrochloride
|
GSK-3008348 hydrochloride is a novel potent, selective integrin αvβ6 antagonist for the treatment of idiopathic pulmonary fibrosis (IPF). |
| PC-60069 |
GSK-3008348
|
GSK-3008348 is a novel potent, selective integrin αvβ6 antagonist for the treatment of idiopathic pulmonary fibrosis (IPF). |
| PC-44703 |
TR-14035
Integrin α4β1/α4β7 inhibitor
|
TR-14035 (TR14035) is a potent, orally bioavailable, dual α4β7/α4β1 integrin antagonist with IC50 of 7/87 nM. |
| PC-45954 |
Zaurategrast
Integrin α4β1/α4β7 inhibitor
|
Zaurategrast (CDP-323, CT7758) is a potent and selective, orally bioavailable α4 integrin (α4β1/VLA-4 and, to a lesser extent, α4β7 integrin) antagonist, an ester prodrug of CT-7758. |
| PC-45519 |
OSU-T315
ILK inhibitor
|
OSU-T315 is a potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 uM. |
| PC-42179 |
GLPG-0187
Integrin inhibitor
|
GLPG-0187 (GLPG0187) is a highly potent, broad spectrum integrin receptor antagonist with IC50 of 1-10 nM for αvβ1, αvβ3, αvβ5, αvβ6, αvβ8 and α5β1. |
| PC-47465 |
Cyclo(RGDfK)
αvβ3 integrin inhibitor
|
Cyclo(RGDfK) is a RGD pipetide, potent and selective αvβ3 integrin inhibitor with Kd of 41.7 nM. |
| PC-21536 |
ATN-161 TFA salt
Integrin inhibitor
|
ATN-161 TFA salt (Ac-PHSCN-NH2) is a small peptide inhibitor of integrin alpha5 beta1 (α5β1) and alphavbeta3 (αvβ3) with binding Kd of 1.0 and 0.6 uM, respectively, inhibits breast cancer growth and metastasis. |
