Chemical Structure : AJM300
CAS No.: 401905-67-7
Catalog No.: PC-35657Not For Human Use, Lab Use Only.
AJM300 (Carotegrast methyl, AJM-300) is a novel potent, selective, oraaly available alpha 4 integrin antagonist fortreatment of active ulcerative colitis.
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AJM300 (Carotegrast methyl, AJM-300) is a novel potent, selective, oraaly available alpha 4 integrin antagonist fortreatment of active ulcerative colitis.
M.Wt | 569.439 | |
Formula | C28H26Cl2N4O5 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
methyl (S)-2-(2,6-dichlorobenzamido)-3-(4-(6-(dimethylamino)-1-methyl-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)phenyl)propanoate |
1. Halland N, et al. ACS Med Chem Lett. 2014 Jan 10;5(2):193-8.
2. Park SC, et al. World J Gastroenterol. 2018 May 7;24(17):1868-1880.
3. Sugiura T, et al. J Crohns Colitis. 2013 Dec;7(11):e533-42.
4. Yoshimura N, et al. Gastroenterology. 2015 Dec;149(7):1775-1783.e2.
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