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AJM300

Chemical Structure : AJM300

CAS No.: 401905-67-7

AJM300 (Carotegrast methyl, AJM-300)

Catalog No.: PC-35657Not For Human Use, Lab Use Only.

AJM300 (Carotegrast methyl, AJM-300) is a novel potent, selective, oraaly available alpha 4 integrin antagonist fortreatment of active ulcerative colitis.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

AJM300 (Carotegrast methyl, AJM-300) is a novel potent, selective, oraaly available alpha 4 integrin antagonist fortreatment of active ulcerative colitis.

Physicochemical Properties

M.Wt 569.439
Formula C28H26Cl2N4O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

methyl (S)-2-(2,6-dichlorobenzamido)-3-(4-(6-(dimethylamino)-1-methyl-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)phenyl)propanoate

References

1. Halland N, et al. ACS Med Chem Lett. 2014 Jan 10;5(2):193-8.

2. Park SC, et al. World J Gastroenterol. 2018 May 7;24(17):1868-1880.

3. Sugiura T, et al. J Crohns Colitis. 2013 Dec;7(11):e533-42.

4. Yoshimura N, et al. Gastroenterology. 2015 Dec;149(7):1775-1783.e2.

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