Chemical Structure : RGDS peptide
CAS No.: 91037-65-9
Catalog No.: PC-42953Not For Human Use, Lab Use Only.
RGDS peptide (Arg-Gly-Asp-Ser) is a integrin binding sequence that inhibits integrin receptor function, a tetrapeptide analogue of the cell attachment site of fibronectin.
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RGDS peptide (Arg-Gly-Asp-Ser) is an integrin binding sequence that inhibits integrin receptor function, a tetrapeptide analogue of the cell attachment site of fibronectin.
RGDS peptide (Arg-Gly-Asp-Ser) decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9.
RGDS peptide (Arg-Gly-Asp-Ser) inhibits thrombin-induced binding of platelets to fibronectin, fibrinogen α, and von Willebrand factor with IC50 of 10 uM.
M.Wt | 433.417 | |
Formula | C15H27N7O8 | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: ≥ 55 mg/mL |
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Chemical Name/SMILES |
L-Serine, L-arginylglycyl-L-α-aspartyl- |
1. Grigoriou V, et al. J Biol Chem. 2005 Jan 21;280(3):1733-9.
2. Moon C, et al. Respir Res. 2009 Mar 9;10:18.
3. Droppelmann CA, et al. J Biol Chem. 2009 May 15;284(20):13551-61.
4. Gartner TK, et al. J Biol Chem. 1985 Oct 5;260(22):11891-4.
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