Catalog No.: PC-42953Not For Human Use, Lab Use Only.
RGDS peptide (Arg-Gly-Asp-Ser) is a integrin binding sequence that inhibits integrin receptor function, a tetrapeptide analogue of the cell attachment site of fibronectin.
RGDS peptide (Arg-Gly-Asp-Ser) is an integrin binding sequence that inhibits integrin receptor function, a tetrapeptide analogue of the cell attachment site of fibronectin.
RGDS peptide (Arg-Gly-Asp-Ser) decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9.
RGDS peptide (Arg-Gly-Asp-Ser) inhibits thrombin-induced binding of platelets to fibronectin, fibrinogen α, and von Willebrand factor with IC50 of 10 uM.
Physicochemical Properties
M.Wt
433.417
Formula
C15H27N7O8
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 55 mg/mL
Chemical Name/SMILES
L-Serine, L-arginylglycyl-L-α-aspartyl-
References
1. Grigoriou V, et al. J Biol Chem. 2005 Jan 21;280(3):1733-9.
2. Moon C, et al. Respir Res. 2009 Mar 9;10:18.
3. Droppelmann CA, et al. J Biol Chem. 2009 May 15;284(20):13551-61.
4. Gartner TK, et al. J Biol Chem. 1985 Oct 5;260(22):11891-4.
