Chemical Structure : Risuteganib
CAS No.: 1307293-62-4
Catalog No.: PC-35165Not For Human Use, Lab Use Only.
Risuteganib (ALG-1001) is a first-in-class, RGD class oligopeptide that inhibits integrin receptors (αvβ3, αvβ5, and α5β1) associated with angiogenesis.
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Risuteganib (ALG-1001) is a first-in-class, RGD class oligopeptide that inhibits integrin receptors (αvβ3, αvβ5, and α5β1) associated with angiogenesis.
ALG1001 inhibits an integrin-mediated pathway of the vitreoretinal interface, connecting the posterior aspect of the vitreous with the internal limiting membrane of the retina.
In blocking this pathway, ALG-1001 helps to achieve vitreous breakdown and separation from the retina.
M.Wt | 637.666 | |
Formula | C22H39N9O11S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
L-Proline, glycyl-L-arginylglycyl-3-sulfo-L-alanyl-L-threonyl- |
1. Yang P, et al. Invest Ophthalmol Vis Sci. 2020 Aug 3;61(10):35.
2. Schneider K, et al. Exp Eye Res. 2021 Feb;203:108287.
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