Cat. No. |
Product Name |
Information |
PC-35546 |
BIO1211
|
BIO1211 (BIO-1211) is a potent, highly specific integrin α4β1 (VLA-4) inhibitor with Kd/IC50 of 20 pM/4 nM for the activated form of α4β1. |
PC-35545 |
DS-70
|
DS-70 (α4 integrin inhibitor DS-70) is a novel potent α/β- peptidomimetic antagonist of α4 integrin, binds to integrin α4β1 with nanomolar affinity. |
PC-35164 |
SF0166
|
SF0166 is a topically administered αvβ3 integrin antagonist, inhibits integrin-ligand interactions with IC50 of 0.6 nM to 13 nM for human αvβ3, αvβ6, and αvβ8. |
PC-35072 |
ER-464195-01
|
ER-464195-01 is a specific, orally active inhibitor that inhibits Calreticulin (CRT) binding to integrin α subunits (ITGAs) with IC50 of 0.17, 0.36, and 0.23 uM in the interaction between CRT and ITGA α4, αL, and αM/α2/α5. |
PC-42953 |
RGDS peptide
|
RGDS peptide (Arg-Gly-Asp-Ser) is a integrin binding sequence that inhibits integrin receptor function, a tetrapeptide analogue of the cell attachment site of fibronectin. |
PC-62071 |
α2β1 integrin-IN-15
|
α2β1 integrin-IN-15 highly potent, selective, allosteric small-molecule inhibitor of integrin α2β1 with IC50 of 12 nM. |
PC-61417 |
JK-273
|
A small molecule inhibitor of α4 integrin-dependent cell migration (IC50=0.5 uM, on the motility of Jurkat T cells) that functions by interacting with γ-parvin. |
PC-61134 |
ML165
|
A high-affinity, selective platelet integrin αIIbβ3 receptor antagonist with IC50 of 96 nM. |
PC-70014 |
BIO-7662
|
A potent, highly selective α4β1 integrin antagonist with Kd of <10 pM. |
PC-45190 |
Tirofiban
|
A potent, selective inhibitor of the platelet fibrinogen receptor GPIIb/IIIa with IC50 of 9 nM, inhibition of platelet aggregation. |
PC-45189 |
Tirofiban hydrochloride monohydrate
|
A potent, selective inhibitor of the platelet fibrinogen receptor GPIIb/IIIa with IC50 of 9 nM, inhibition of platelet aggregation. |
PC-44703 |
TR-14035
|
A potent, orally bioavailable, dual α4β7/α4β1 integrin antagonist with IC50 of 7/87 nM. |