| Cat. No. |
Product Name |
Information |
| PC-61133 |
RUC-4
|
Zalunfiban (RUC-4) is a potent, selective, non-RGD-mimetic αIIbβ3 integrin receptor antagonist with IC50 of 45 nM, with no activity on αVβ3 receptors. |
| PC-60253 |
Leukadherin-1
CD11b agonist
|
Leukadherin-1 (LA1) is a small molecule allosteric agonist of integrin CD11b/CD18 (CR3), increases CD11b/CD18-dependent cell adhesion to fibrinogen (EC50=4 uM). |
| PC-70068 |
Cyclo(RGDyK)
αvβ3 integrin inhibitor
|
Cyclo(RGDyK) (Cyclic Arg-Gly-Asp-D-Tyr-Lys) is a cyclic derivative of RGD, potent, selective αVβ3 integrin inhibitor with IC50 of 20 nM. |
| PC-70014 |
BIO-7662
Integrin α4β1 inhibitor
|
BIO-7662 (BIO7662) is a potent, highly selective α4β1 integrin antagonist with Kd of <10 pM. |
| PC-60070 |
GSK3008348 hydrochloride
αvβ6 integrin inhibitor
|
GSK3008348 hydrochloride is a potent, selective, RGD-mimetic integrin αvβ6 antagonist with KD value of 9.5 pM and 4.8 pM for αvβ6 in normal and IPF human lung tissue membrane preparations. |
| PC-60069 |
GSK3008348
αvβ6 integrin inhibitor
|
GSK3008348 is a potent, selective, RGD-mimetic integrin αvβ6 antagonist with KD value of 9.5 pM and 4.8 pM for αvβ6 in normal and IPF human lung tissue membrane preparations. |
| PC-45190 |
Tirofiban
GPIIb/IIIa inhibitor
|
Tirofiban (L700462, MK-383, MK-0383) is a potent, selective inhibitor of the platelet fibrinogen receptor GPIIb/IIIa with IC50 of 9 nM, inhibition of platelet aggregation. |
| PC-45189 |
Tirofiban hydrochloride monohydrate
GPIIb/IIIa inhibitor
|
Tirofiban hydrochloride monohydrate (L700462, MK-383, MK-0383) is a potent, selective inhibitor of the platelet fibrinogen receptor GPIIb/IIIa with IC50 of 9 nM, inhibition of platelet aggregation. |
| PC-44703 |
TR-14035
Integrin α4β1/α4β7 inhibitor
|
TR-14035 (TR14035) is a potent, orally bioavailable, dual α4β7/α4β1 integrin antagonist with IC50 of 7/87 nM. |
| PC-45616 |
Lifitegrast
LFA-1/ICAM-1 inhibitor
|
Lifitegrast (SAR1118) is a potent LFA-1/ICAM-1 antagonist with IC50 of 9 nM in HuT78 cells. |
| PC-45511 |
Integrin-IN-27
αvβ3 integrin inhibitor
|
Integrin-IN-27 is a potent integrin αvβ3 antagonist with IC50 of 18 nM. |
| PC-45954 |
Zaurategrast
Integrin α4β1/α4β7 inhibitor
|
Zaurategrast (CDP-323, CT7758) is a potent and selective, orally bioavailable α4 integrin (α4β1/VLA-4 and, to a lesser extent, α4β7 integrin) antagonist, an ester prodrug of CT-7758. |
