Chemical Structure : Tirofiban hydrochloride monohydrate
CAS No.: 150915-40-5
Catalog No.: PC-45189Not For Human Use, Lab Use Only.
Tirofiban hydrochloride monohydrate (L700462, MK-383, MK-0383) is a potent, selective inhibitor of the platelet fibrinogen receptor GPIIb/IIIa with IC50 of 9 nM, inhibition of platelet aggregation.
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50 mg | $138 | In stock | |
100 mg | $218 | In stock | |
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Tirofiban hydrochloride monohydrate (L700462, MK-383, MK-0383) is a potent, selective inhibitor of the platelet fibrinogen receptor GPIIb/IIIa with IC50 of 9 nM, inhibition of platelet aggregation.
Tirofiban displays > 24,000-fold over human umbilical vein endothelial cell fibrinogen receptors.
Tirofiban inhibits ex vivo platelet aggregation induced by ADP in anesthetized dogs.
M.Wt | 495.0728 | |
Formula | C22H39ClN2O6S | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: 12 mg/mL |
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Chemical Name/SMILES |
L-Tyrosine, N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-, hydrochloride, hydrate (1:1:1) |
1. Hartman GD, et al. J Med Chem. 1992 Nov 27;35(24):4640-2.
2. Lynch JJ Jr, et al. J Pharmacol Exp Ther. 1995 Jan;272(1):20-32.
3. Cook NS, et al. Thromb Haemost. 1993 Nov 15;70(5):838-47.
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