RUC-4 |CAS:1448313-27-6 Probechem Biochemicals

Chemical Structure : RUC-4

CAS No.: 1448313-27-6

RUC-4 (RUC4;Zalunfiban)

Catalog No.: PC-61133Not For Human Use, Lab Use Only.

Zalunfiban (RUC-4) is a potent, selective, non-RGD-mimetic αIIbβ3 integrin receptor antagonist with IC50 of 45 nM, with no activity on αVβ3 receptors.

Packing	Price	Stock
10 mg	$288	In stock
25 mg	$498	In stock
100 mg	$1280	In stock
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Biological Activity

Zalunfiban (RUC-4) is a potent, selective, non-RGD-mimetic αIIbβ3 integrin receptor antagonist with IC50 of 45 nM, with no activity on αVβ3 receptors.

Physicochemical Properties

M.Wt	386.434
Formula	C16H18N8O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-amino-N-(5-(5-oxo-7-(piperazin-1-yl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl)pyridin-3-yl)acetamide

References

1. Miller LM, et al. J Med Chem. 2017 Apr 27;60(8):3241-3251.

2. Jiang JK, et al. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1148-53.

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RUC-4 (RUC4;Zalunfiban)

Biological Activity

Physicochemical Properties

References

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