Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Cytoskeleton/Cell Adhesion Molecules-Integrin-Tirofiban
Tirofiban

Chemical Structure : Tirofiban

CAS No.: 144494-65-5

Tirofiban (L700462, MK-383, MK-0383)

Catalog No.: PC-45190Not For Human Use, Lab Use Only.

Tirofiban (L700462, MK-383, MK-0383) is a potent, selective inhibitor of the platelet fibrinogen receptor GPIIb/IIIa with IC50 of 9 nM, inhibition of platelet aggregation.

Packing Price Stock Quantity
25 mg $98 In stock
50 mg $138 In stock
100 mg $228 In stock
250 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Tirofiban (L700462, MK-383, MK-0383) is a potent, selective inhibitor of the platelet fibrinogen receptor GPIIb/IIIa with IC50 of 9 nM, inhibition of platelet aggregation.
Tirofiban displays > 24,000-fold over human umbilical vein endothelial cell fibrinogen receptors.
Tirofiban inhibits ex vivo platelet aggregation induced by ADP in anesthetized dogs.

Physicochemical Properties

M.Wt 440.5966
Formula C22H36N2O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: < 1 mg/mL

Chemical Name/SMILES

L-Tyrosine, N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-

References

1. Hartman GD, et al. J Med Chem. 1992 Nov 27;35(24):4640-2.

2. Lynch JJ Jr, et al. J Pharmacol Exp Ther. 1995 Jan;272(1):20-32.

3. Cook NS, et al. Thromb Haemost. 1993 Nov 15;70(5):838-47.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: