Chemical Structure : TR-14035
CAS No.:
232271-19-1
TR-14035
(TR 14035;TR14035)
Catalog No. : PC-44703Not For Human Use, Lab Use Only.
TR-14035 (TR14035) is a potent, orally bioavailable, dual α4β7/α4β1 integrin antagonist with IC50 of 7/87 nM.
Packing Price Stock Quantity 5 mg $158 In stock 0 1 2 3 4 5 10 mg $248 In stock 0 1 2 3 4 5 25 mg $398 In stock 0 1 2 3 4 5 50 mg $598 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4470301
Biological Activity
TR-14035 (TR14035) is a potent, orally bioavailable, dual α4β7/α4β1 integrin antagonist with IC50 of 7/87 nM.
Physicochemical Properties
M.Wt
474.3333
Formula
C24H21Cl2NO5
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO：≥ 41 mg/mL
Chemical Name/SMILES
[1,1'-Biphenyl]-4-propanoic acid, α-[(2,6-dichlorobenzoyl)amino]-2',6'-dimethoxy-,(αS)-
References
1. Sircar I, et al. Bioorg Med Chem
2. Cortijo J, et al. Br J Pharmacol
3. Tsuda-Tsukimoto M, et al. Pharm Res
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