| Cat. No. |
Product Name |
Information |
| PC-45616 |
Lifitegrast
LFA-1/ICAM-1 inhibitor
|
Lifitegrast (SAR1118) is a potent LFA-1/ICAM-1 antagonist with IC50 of 9 nM in HuT78 cells. |
| PC-45511 |
Integrin-IN-27
αvβ3 integrin inhibitor
|
Integrin-IN-27 is a potent integrin αvβ3 antagonist with IC50 of 18 nM. |
| PC-45954 |
Zaurategrast
Integrin α4β1/α4β7 inhibitor
|
Zaurategrast (CDP-323, CT7758) is a potent and selective, orally bioavailable α4 integrin (α4β1/VLA-4 and, to a lesser extent, α4β7 integrin) antagonist, an ester prodrug of CT-7758. |
| PC-45519 |
OSU-T315
ILK inhibitor
|
OSU-T315 is a potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 uM. |
| PC-45501 |
CWHM-12
αV integrins inhibitor
|
CWHM-12 is a potent RGD peptidomimetic inhibitor of αv integrins with IC50s of 1.8/0.8/61/1.5/0.2 nM for αvβ1/αvβ3/αvβ5/αvβ6/αvβ8. |
| PC-42179 |
GLPG0187
Integrin inhibitor
|
GLPG0187 (GLPG 0187) is a highly potent, broad spectrum integrin receptor antagonist with IC50 of 1-10 nM for αvβ1, αvβ3, αvβ5, αvβ6, αvβ8 and α5β1. |
| PC-47465 |
Cyclo(RGDfK)
αvβ3 integrin inhibitor
|
Cyclo(RGDfK) is a RGD pipetide, potent and selective αvβ3 integrin inhibitor with Kd of 41.7 nM. |
| PC-23193 |
Carotegrast
α4 integrin inhibitor
|
Carotegrast (HCA2969) is a novel potent, selective, oraaly available alpha 4 integrin antagonist. |
| PC-73164 |
Cilengitide
Integrin inhibitor
|
Cilengitide (EMD 121974) is a potent, selective, cyclic Arg-Gly-Asp peptide inhibitor of integrins αvβ3 and αvβ5 with IC50 4.1 and 70 nM, respectively. |
