Chemical Structure : Lifitegrast
CAS No.:
1025967-78-5
Lifitegrast
(SAR1118, SAR-1118, SHP-606)
Catalog No. : PC-45616Not For Human Use, Lab Use Only.
Lifitegrast (SAR1118) is a potent LFA-1/ICAM-1 antagonist with IC50 of 9 nM in HuT78 cells.
Packing Price Stock Quantity 10 mg $88 In stock 0 1 2 3 4 5 25 mg $138 In stock 0 1 2 3 4 5 50 mg $218 In stock 0 1 2 3 4 5 100 mg $358 In stock 0 1 2 3 4 5 250 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4561601
Biological Activity
Lifitegrast (SAR1118) is a potent LFA-1/ICAM-1 antagonist with IC50 of 9 nM in HuT78 cells.
Physicochemical Properties
M.Wt
615.4811
Formula
C29H24Cl2N2O7S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 29 mg/mL
Chemical Name/SMILES
L-Phenylalanine, N-[[2-(6-benzofuranylcarbonyl)-5,7-dichloro-1,2,3,4-tetrahydro-6-isoquinolinyl]carbonyl]-3-(methylsulfonyl)-
References
1. Zhong M, et al. ACS Med Chem Lett.
2. Sun Y, et al. J Ocul Pharmacol Ther
3. Semba CP, et al. Clin Ophthalmol.
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