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Emvistegrast

Chemical Structure : Emvistegrast

CAS No.: 2417352-91-9

Emvistegrast (GS-1427)

Catalog No.: PC-25046Not For Human Use, Lab Use Only.

Emvistegrast (GS-1427) is an oral prodrug that is rapidly converted to the active species GS-1069518, a potent and selective α4β7 integrin inhibitor.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Emvistegrast (GS-1427) is an oral prodrug that is rapidly converted to the active species GS-1069518, a potent and selective α4β7 integrin inhibitor.

Physicochemical Properties

M.Wt 708.67
Formula C35H32F4N6O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

ethyl (S)-2-(2-fluoro-6-methyl-4-((R)-3-(trifluoromethyl)morpholino)benzamido)-3-(8-(1-methyl-2,4-dioxo-1,4-dihydropyrido[3,4-d]pyrimidin-3(2H)-yl)quinolin-5-yl)propanoate

References

1. Patent WO2020092375 A1.

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