Chemical Structure : Cyclo(RGDfK)
CAS No.: 161552-03-0
Catalog No.: PC-47465Not For Human Use, Lab Use Only.
Cyclo(RGDfK) is a RGD pipetide, potent and selective αvβ3 integrin inhibitor with Kd of 41.7 nM.
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Cyclo(RGDfK) is a RGD pipetide, potent and selective αvβ3 integrin inhibitor with Kd of 41.7 nM.
Cyclo(RGDfK) shows strong inhibitory effect on the proliferation of T-24 cells.
Cyclo(RGDfK) induces less tumor progression, less tumor metabolic activity, fewer intratumoral vessels in mice model.
M.Wt | 603.6705 | |
Formula | C27H41N9O7 | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: ≥150 mg/mL |
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Chemical Name/SMILES |
Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-lysyl) |
1. Sancey L, et al. Mol Ther. 2009, 17(5), 837-843.
2. Zhou D, et al. J Control Release. 2013, 169(3), 204-210.
3. Vilchis-Juarez A, et al. J Biomed Nanotechnol. 2014 Mar;10(3):393-404.
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