Chemical Structure : CWHM-12
CAS No.:
1564286-55-0
CWHM-12
(CWHM12)
Catalog No. : PC-45501Not For Human Use, Lab Use Only.
CWHM-12 is a potent RGD peptidomimetic inhibitor of αv integrins with IC50s of 1.8/0.8/61/1.5/0.2 nM for αvβ1/αvβ3/αvβ5/αvβ6/αvβ8.
Packing Price Stock Quantity 2 mg $78 In stock 0 1 2 3 4 5 5 mg $118 In stock 0 1 2 3 4 5 10 mg $178 In stock 0 1 2 3 4 5 25 mg $298 In stock 0 1 2 3 4 5 50 mg $458 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4550101
Biological Activity
CWHM-12 is a potent RGD peptidomimetic inhibitor of αV integrins with IC50s of 1.8/0.8/61/1.5/0.2 nM for αvβ1/αvβ3/αvβ5/αvβ6/αvβ8.
Physicochemical Properties
M.Wt
590.4662
Formula
C26H32BrN5O6
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: 10.5 mg/mL
Chemical Name/SMILES
β-Alanine, N-[3-hydroxy-5-[(1,4,5,6-tetrahydro-5-hydroxy-2-pyrimidinyl)amino]benzoyl]glycyl-3-[3-bromo-5-(1,1-dimethylethyl)phenyl]-, (3S)-
References
1. Henderson NC, et al. Nat Med.
2. Ulmasov B, et al. Cell Mol Gastroenterol Hepatol.
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