IVL745 | VLA-4 inhibitor | Probechem Biochemicals

Chemical Structure : IVL745

IVL745 (IVL-745)

Catalog No.: PC-49345Not For Human Use, Lab Use Only.

IVL745 (IVL-745) is a small molecule very late antigen (VLA-4) antagonist with IC50 of 20 nM and 2 nM for adhesion to VCAM-1 and fibronectin, respectively.

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Biological Activity

IVL745 (IVL-745) is a small molecule very late antigen (VLA-4) antagonist with IC50 of 20 nM and 2 nM for adhesion to VCAM-1 and fibronectin, respectively.

Physicochemical Properties

M.Wt	592.649
Formula	C31H36N4O8
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(N-(3,4-dimethoxybenzyl)-2-(2-(3-methoxy-4-(3-(o-tolyl)ureido)phenyl)acetamido)acetamido)propanoic acid

References

1. Norris V, et al. J Allergy Clin Immunol. 2005 Oct;116(4):761-7.

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IVL745 (IVL-745)

Biological Activity

Physicochemical Properties

References

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