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IVL745

Chemical Structure : IVL745

CAS No.: 229627-58-1

IVL745 (IVL-745)

Catalog No.: PC-49345Not For Human Use, Lab Use Only.

IVL745 (IVL-745) is a small molecule very late antigen (VLA-4) antagonist with IC50 of 20 nM and 2 nM for adhesion to VCAM-1 and fibronectin, respectively.

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    Biological Activity

    IVL745 (IVL-745) is a small molecule very late antigen (VLA-4) antagonist with IC50 of 20 nM and 2 nM for adhesion to VCAM-1 and fibronectin, respectively.

    Physicochemical Properties

    M.Wt 592.649
    Formula C31H36N4O8
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    3-(N-(3,4-dimethoxybenzyl)-2-(2-(3-methoxy-4-(3-(o-tolyl)ureido)phenyl)acetamido)acetamido)propanoic acid

    References

    1. Norris V, et al. J Allergy Clin Immunol. 2005 Oct;116(4):761-7.

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