MORF-627 | αvβ6 integrin inhibitor | Probechem Biochemicals

Chemical Structure : MORF-627

Catalog No.: PC-23275Not For Human Use, Lab Use Only.

MORF-627 is a highly selective inhibitor of integrin αvβ6 with IC50 of 1.1 nM, >300-fold selective over αvβ1 and αvβ8.

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Biological Activity

MORF-627 is a highly selective inhibitor of integrin αvβ6 with IC50 of 1.1 nM, >300-fold selective over αvβ1 and αvβ8.

M.Wt	537.68
Formula	C31H40FN3O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-(5-fluoro-2-((S)-5-oxaspiro[2.5]octan-6-yl)phenyl)-2-((R)-3-(4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butoxy)pyrrolidin-1-yl)acetic acid

1. Harrison BA, et al. J Med Chem. 2024 Oct 24. doi: 10.1021/acs.jmedchem.4c01851.