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MORF-627

Chemical Structure : MORF-627

CAS No.: 2412688-16-3

MORF-627 (MORF627)

Catalog No.: PC-23275Not For Human Use, Lab Use Only.

MORF-627 is a highly selective inhibitor of integrin αvβ6 with IC50 of 1.1 nM, >300-fold selective over αvβ1 and αvβ8.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    MORF-627 is a highly selective inhibitor of integrin αvβ6 with IC50 of 1.1 nM, >300-fold selective over αvβ1 and αvβ8.

    Physicochemical Properties

    M.Wt 537.68
    Formula C31H40FN3O4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (S)-2-(5-fluoro-2-((S)-5-oxaspiro[2.5]octan-6-yl)phenyl)-2-((R)-3-(4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butoxy)pyrrolidin-1-yl)acetic acid

    References

    1. Harrison BA, et al. J Med Chem. 2024 Oct 24. doi: 10.1021/acs.jmedchem.4c01851.

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