| Cat. No. |
Product Name |
Information |
| PC-21352 |
Ombitasvir
HCV NS5A inhibitor
|
Ombitasvir (ABT-267) is a potent, selective pan-genotypic inhibitor of HCV NS5A with EC50 of 1.7-19.3 pM against GT1a, -1b, -2a, -2b, -3a, -4a, and -5a and 366 pM against GT6a. |
| PC-20275 |
Nesbuvir
HCV NS5B inhibitor
|
Nesbuvir (HCV-796) is a selective, non-nucleoside HCV nonstructural protein 5B (NS5B) polymerase inhibitor with IC50 of 0.01-0.14 uM for genotype 1, EC50 of 5 nM and 9 nM against genotype 1a and 1b replicon. |
| PC-72397 |
GSK2818713
HCV NS5A inhibitor
|
GSK2818713 (GSK-2818713) is a nonstructural protein 5A (NS5A) HCV inhibitor with broad genotype coverage. |
| PC-35585 |
Cyclophilin inhibitor C31
|
Cyclophilin inhibitor C31 (SMCypI C31) is a small-molecule cyclophilin (CypA) inhibitor (SMCypI) with PPIase inhibition IC50 of 0.1 uM, displays anti-HCV activity (HCV Gt1b replicon EC50=0.4 uM) and disrupts the CypA-NS5A interaction. |
| PC-35444 |
Coblopasvir
|
Coblopasvir (KW136, KW-136) is a novel HCV NS5A inhibitor under development for treatment of HCV infection.. |
| PC-35056 |
Ciluprevir
|
Ciluprevir (BILN2061) is a potent HCV NS3/4A protease inhibitor with Ki of 0.66 and 0.30 nM for NS3-NS4A protease of HCV 1b and HCV 1a, respectively. |
| PC-35032 |
BI-1388
|
BI-1388 is a potent, specific, macrocyclic inhibitor of HCV NS3 protease, inhibits viral replication for various HCV genotypes and for resistant mutants D168V and R155K. |
| PC-63573 |
MK-3281
|
MK-3281 is a potent and orally bioavailable inhibitor of HCV NS5B polymerase with IC50 of 6 nM. |
| PC-63572 |
Beclabuvir hydrochloride
|
Beclabuvir (BMS-791325) is a potent allosteric inhibitor of HCV NS5B polymerase with EC50 of 6 and 3 nM for genotype 1b and 1a in FRET assays, respectively. |
| PC-63571 |
Beclabuvir
|
Beclabuvir (BMS-791325) is a potent allosteric inhibitor of HCV NS5B polymerase with EC50 of 6 and 3 nM for genotype 1b and 1a in FRET assays, respectively. |
| PC-63558 |
BI 207524
|
BI 207524 is a potent inhibitor of HCV thumb pocket 1 NS5B inhibitor with IC50 of 84 nM, inhibits Gt 1a/1b replicons with EC50 of 29/11 nM.. |
| PC-43491 |
Anguizole
|
Anguizole is a HCV NS4B inhibitor targeting second amphipathic helix of NS4B (NS4B-AH2), blocks genotype 1b HCV replication with EC50 of 310 nM. |
