| Cat. No. |
Product Name |
Information |
| PC-63018 |
Azvudine
HCV NS5B inhibitor
|
Azvudine (RO 0622) is a potent HCV NS5B RNA polymerase inhibitor, inhibits HCV replication in the replicon system with IC50 of 24 nM. |
| PC-63008 |
Radalbuvir
HCV NS5B inhibitor
|
Radalbuvir (GS-9669) is a highly optimized thumb site II nonnucleoside inhibitor of HCV NS5B polymerase with binding affinity of 1.35 nM for genotype 1b. |
| PC-63007 |
Vedroprevir
HCV NS3/4A inhibitor
|
Vedroprevir (GS-9451) is a potent HCV NS3/4A protease inhibitor with Ki of 0.41 nM, inhibits HCV GT-1b NS3/4A with IC50 of 3.2 nM in enzymatic assays. |
| PC-62847 |
BMS-961955
HCV NS5B inhibitor
|
BMS-961955 is an potent, allosteric inhibitor of HCV NS5B polymerase with EC50 of 7.9/4.3 nM for GT 1b/1a replicon respectively. |
| PC-62828 |
IDX-375
HCV NS5B inhibitor
|
IDX-375 is a novel potent, non-nucleoside, allosteric HCV NS5B RdRp inhibitor with IC50 of 15 nM and 5 nM for 1a-H77 HCV NS5B polymerase and 1b-J4 HCV NS5B polymerase, respectively. |
| PC-62784 |
IDX17119
HCV NS5B inhibitor
|
IDX17119 is a potent, non-nucleoside, HCV NS5B RdRp inhibitor with IC50 of 0.4 nM in replicon luciferase assays. |
| PC-62637 |
ABT-072
HCV NS5B inhibitor
|
ABT-072 is a novel, orally bioavailable non-nucleoside HCV NS5B polymerase inhibitor with EC50 of 0.3 nM (GT1b). |
| PC-62618 |
PTC725
HCV NS4B inhibitor
|
PTC725 is a potent, selective, and orally bioavailable inhibitor of HCV NS4B, inhibits HCV 1b (Con1) replicons with EC50 of 1.7 nM. |
| PC-61941 |
Glecaprevir
HCV NS3/4A inhibitor
|
Glecaprevir (ABT-493, A1282576) is a potent HCV NS3/4A protease inhibitor with pan-genotypic activity, inhibits NS3/4A proteases from HCV genotypes 1-6 in vitro with IC50 of 3.5-11.3 nM. |
| PC-61888 |
Filibuvir
HCV NS5B inhibitor
|
Filibuvir (PF-00868554, PF-868554) is a nonnucleoside, potent and selective, orally available HCV NS5B inhibitor with IC50 of 19 nM, EC50 of 75 nM (genotype 1b-Con1 replicon). |
| PC-61873 |
Ravidasvir dihydrochloride
HCV NS5A inhibitor
|
Ravidasvir (PPI-668, BI 238630) is a potent pan-genotypic HCV NS5A inhibitor with IC50 of 0.12/0.01/1.14 nM for HCV gt-1a/1b/3a in replicon luciferase assay. |
| PC-61872 |
Ravidasvir
HCV NS5A inhibitor
|
Ravidasvir (PPI-668, BI 238630) is a potent pan-genotypic HCV NS5A inhibitor with IC50 of 0.12/0.01/1.14 nM for HCV gt-1a/1b/3a in replicon luciferase assay. |
