Chemical Structure : Pibrentasvir
CAS No.:
1353900-92-1
Pibrentasvir
(ABT-530, ABT530)
Catalog No. : PC-63073Not For Human Use, Lab Use Only.
Pibrentasvir (ABT-530) is a novel and pan-genotypic HCV NS5A inhibitor with EC50 of 1.4-5.0 pM against HCV replicons containing NS5A genotypes 1-6.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6307301
Biological Activity
Pibrentasvir (ABT-530) is a novel and pan-genotypic HCV NS5A inhibitor with EC50 of 1.4-5.0 pM against HCV replicons containing NS5A genotypes 1-6.
Physicochemical Properties
M.Wt
1113.2
Formula
C57H65F5N10O8
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Dimethyl ((2S,2'S,3R,3'R)-((2S,2'S)-(((2R,5R)-1-(3,5-difluoro-4-(4-(4-fluorophenyl)piperidin-1-yl)phenyl)pyrrolidine-2,5-diyl)bis(6-fluoro-1H-benzo[d]imidazole-5,2-diyl))bis(pyrrolidine-2,1-diyl))bis(3-methoxy-1-oxobutane-1,2-diyl))dicarbamate
References
1. Lawitz EJ, et al. Antimicrob Agents Chemother
2. Poordad F, et al. Liver Int.
3. Ng TI, et al. Antimicrob Agents Chemother.
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