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ABT-072

Chemical Structure : ABT-072

CAS No.: 1132936-00-5

ABT-072 (ABT072)

Catalog No.: PC-62637Not For Human Use, Lab Use Only.

ABT-072 is a novel, orally bioavailable non-nucleoside HCV NS5B polymerase inhibitor with EC50 of 0.3 nM (GT1b).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    ABT-072 is a novel, orally bioavailable non-nucleoside HCV NS5B polymerase inhibitor with EC50 of 0.3 nM (GT1b).
    ABT-072 is a new direct-acting antivirals (DAAs) for the treatment of HCV infection.

    Physicochemical Properties

    M.Wt 469.556
    Formula C24H27N3O5S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (E)-N-(4-(3-(tert-butyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxystyryl)phenyl)methanesulfonamide

    References

    1. Randolph JT, et al. J Med Chem. 2018 Feb 8;61(3):1153-1163.

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