| Cat. No. |
Product Name |
Information |
| PC-60009 |
INX-08189
HCV NS5B inhibitor
|
INX-08189 (BMS-986094) is a phosphoramidate prodrug of O-6-methyl-2-C-methyl guanosine, potent inhibitor of HCV NS5B polymerase with IC50 of 10 nM in replicon assay. |
| PC-42588 |
Balapiravir
HCV NS5B inhibitor
|
Balapiravir (R-1626, Ro 4588161) is the prodrug of R1479, a potent, specific and oral HCV NS5B polymerase inhibitor. |
| PC-42479 |
Mericitabine
HCV NS5B inhibitor
|
Mericitabine (RG-7128, R-7128, PSI-6130 diisobutyrate) is the prodrug of PSI-6130, a potent, specific inhibitor of HCV RNA synthesis by inhibiting the NS5B RNA polymerase. |
| PC-42412 |
PSI-6130
HCV NS5B inhibitor
|
PSI-6130 (R-1656) is a potent, specific inhibitor of HCV RNA synthesis by inhibiting the NS5B RNA polymerase (EC90=4.6 uM in replicon assay). |
| PC-42589 |
R-1479
HCV NS5B inhibitor
|
R-1479 is a potent, specific inhibitor of HCV NS5B polymerase and HCV replication (IC50=1.28 uM, replicon assay). |
| PC-42477 |
Boceprevir
HCV NS3 protease inhibitor
|
Boceprevir (EBP520, SCH503034) is a potent, selective, orally bioavailable HCV NS3 protease with Ki of 14 nM, EC90 of 350 nM in cell replicon assays. |
| PC-42481 |
Vaniprevir
HCV NS3/4A inhibitor
|
Vaniprevir (MK-7009) is a potent, selective, orally available inhibitor of HCV NS3/4A protease with Ki of 0.05 and 0.9 nM for GT1b and 2a protease, respectively. |
| PC-42476 |
Telaprevir
HCV NS3/4A inhibitor
|
Telaprevir (VX-950) is a potent, selective, covalent, orally bioavailable inhibitor of HCV NS3/4A protease with Ki of 7 nM. |
| PC-42515 |
Narlaprevir
HCV NS3 protease inhibitor
|
Narlaprevir (SCH900518) is a potent, second generation HCV NS3 serine protease inhibitor with Ki of 6 nM. |
| PC-42480 |
Simeprevir
HCV NS3/4A inhibitor
|
Simeprevir (TMC435, TMC435350) is a potent, orally available inhibitor of HCV NS3/4A protease with Ki of 0.36 nM, replicon EC50 of 7.8 nM. |
| PC-42478 |
Danoprevir
HCV NS3/4A inhibitor
|
Danoprevir (ITMN-191, R-7227) is a potent, highly selective, orally available, peptidomimetic HCV NS3/4A protease inhibitor with IC50 of 0.2-0.4 nM (GT1a, 1b, 4, 5 and 6), 1.6 nM (GT2b). |
| PC-42722 |
RO-9187
HCV NS5B inhibitor
|
RO-9187 is a potent HCV NS5B RNA polymerase inhibitor, inhibits HCV replication in the replicon system with IC50 of 171 nM. |
