BMT-052 | HCV NS5B inhibitor | Probechem Biochemicals

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Chemical Structure : BMT-052

BMT-052 (BMT052, BMT 052)

Catalog No.: PC-60424Not For Human Use, Lab Use Only.

BMT-052 is a second generation, orally biovailable pan-genotypic HCV NS5B polymerase inhibitor with EC50 of 1-10 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BMT-052 is a second generation, orally biovailable pan-genotypic HCV NS5B polymerase inhibitor with EC50 of 1-10 nM.
BMT-052 exhibits good genotype coverage, low clearance, a moderate volume of distribution and no cytotoxicity (CC50>100 uM).

Physicochemical Properties

M.Wt	635.6235
Formula	C30H17D9F4N6O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(5-((2-(1,2,4-oxadiazol-3-yl)propan-2-yl-1,1,1,3,3,3-d6)carbamoyl)-6-(methoxy-d3)pyridin-3-yl)-2-(4-fluorophenyl)-N-methyl-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide

References

1. Parcella K, et al. ACS Med Chem Lett. 2017 Jun 29;8(7):771-774.

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BMT-052 (BMT052, BMT 052)

Biological Activity

Physicochemical Properties

References

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