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Balapiravir

Chemical Structure : Balapiravir

CAS No.: 690270-29-2

Balapiravir (R-1626, R1626, Ro 4588161, Ro-4588161)

Catalog No.: PC-42588Not For Human Use, Lab Use Only.

Balapiravir (R-1626, Ro 4588161) is the prodrug of R1479, a potent, specific and oral HCV NS5B polymerase inhibitor.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Balapiravir (R-1626, Ro 4588161) is the prodrug of R1479, a potent, specific and oral HCV NS5B polymerase inhibitor.
Balapiravir demonstrates strong capacity to inhibit HCV replication in vitro and in vivo, without the rapid development of viral resistance.

Physicochemical Properties

M.Wt 494.4983
Formula C21H30N6O8
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 100 mg/mL

Chemical Name/SMILES

Cytidine, 4'-C-azido-, 2',3',5'-tris(2-methylpropanoate)

References

1. Roberts SK, et al. Hepatology. 2008 Aug;48(2):398-406.

2. McCown MF, et al. Antimicrob Agents Chemother. 2008 May;52(5):1604-12.

3. Chen YL, et al. J Virol. 2014 Feb;88(3):1740-7.

4. Toniutto P, et al. IDrugs. 2008 Oct;11(10):738-49.

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