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Mericitabine

Chemical Structure : Mericitabine

CAS No.: 940908-79-2

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Mericitabine (RG-7128, R-7128, PSI-6130 diisobutyrate)

Catalog No.: PC-42479Not For Human Use, Lab Use Only.

Mericitabine (RG-7128, R-7128, PSI-6130 diisobutyrate) is the prodrug of PSI-6130, a potent, specific inhibitor of HCV RNA synthesis by inhibiting the NS5B RNA polymerase.

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5 mg $148 In stock
10 mg $228 In stock
25 mg $378 In stock
50 mg $588 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Mericitabine (RG-7128, R-7128, PSI-6130 diisobutyrate) is the prodrug of PSI-6130, a potent, specific inhibitor of HCV RNA synthesis by inhibiting the NS5B RNA polymerase.

Physicochemical Properties

M.Wt 399.4139
Formula C18H26FN3O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Cytidine, 2'-deoxy-2'-fluoro-2'-methyl-, 3',5'-bis(2-methylpropanoate), (2'R)-

References

1. McCown MF, et al. Antimicrob Agents Chemother. 2008 May;52(5):1604-12.

2. Ali S, et al. Antimicrob Agents Chemother. 2008 Dec;52(12):4356-69.

3. Le Pogam S, et al. J Infect Dis. 2010 Nov 15;202(10):1510-9.

4. Guedj J, et al. Hepatology. 2012 Apr;55(4):1030-7.

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