Catalog No.: PC-42481Not For Human Use, Lab Use Only.
Vaniprevir (MK-7009) is a potent, selective, orally available inhibitor of HCV NS3/4A protease with Ki of 0.05 and 0.9 nM for GT1b and 2a protease, respectively.
Vaniprevir (MK-7009) is a potent, selective, orally available inhibitor of HCV NS3/4A protease with Ki of 0.05 and 0.9 nM for GT1b and 2a protease, respectively.
Vaniprevir (MK-7009) displays excellent selectivity against both a range of human proteases and a broad panel of pharmacologically relevant targets.
Vaniprevir (MK-7009) has replicon EC50 of 3 and 9 nM for GT1b and 2a, respectively, has good plasma exposure and excellent liver exposure in multiple species.
