GSK-625433 | HCV NS5B inhibitor | Probechem Biochemicals

Chemical Structure : GSK-625433

GSK-625433 (GSK 625433, GSK625433)

Catalog No.: PC-60425Not For Human Use, Lab Use Only.

GSK-625433 is highly potent, selective HCV NS5B polymerase inhibitor for treatment of HCV infection, inhibits the polymerase of both HCV genotypes 1a and 1b.

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Biological Activity

GSK-625433 is highly potent, selective HCV NS5B polymerase inhibitor for treatment of HCV infection, inhibits the polymerase of both HCV genotypes 1a and 1b.

Physicochemical Properties

M.Wt	512.62
Formula	C26H32N4O5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(2R,4R,5S)-1-(4-tert-butyl-3-methoxybenzoyl)-4-(methoxymethyl)-2-(pyrazol-1-ylmethyl)-5-(1,3-thiazol-2-yl)pyrrolidine-2-carboxylic acid

References

1. Parcella K, et al. ACS Med Chem Lett. 2017 Jun 29;8(7):771-774.

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GSK-625433 (GSK 625433, GSK625433)

Biological Activity

Physicochemical Properties

References

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