| Cat. No. |
Product Name |
Information |
| PC-61524 |
Samatasvir
HCV NS5A inhibitor
|
Samatasvir (IDX719) is a highly potent, selective inhibitor of HCV NS5A that effectively inhibits HCV genotype 1-5 replicons with EC50 of 2-24 pM. |
| PC-61523 |
TD-6450
HCV NS5A inhibitor
|
TD-6450 is a next generation, potent HCV NS5A inhibitor that has potent antiviral activity against HCV infection. |
| PC-61440 |
Voxilaprevir
HCV NS3/4A inhibitor
|
Voxilaprevir (GS-9857) is a potent HCV NS3/4A protease inhibitor that is used in combination with sofosbuvir and velpatasvir for treatment of HCV infection. |
| PC-61414 |
Uprifosbuvir
HCV NS5B inhibitor
|
Uprifosbuvir (MK3682, IDX 21437) is a novel uridine nucleotide analog HCV NS5B polymerase inhibitor for treatment of HCV infection combined with Grazoprevir and Ruzasvir. |
| PC-60953 |
Faldaprevir
HCV NS3/4A inhibitor
|
Faldaprevir (BI-201335) is a potent, selective noncovalent competitive inhibitor of HCV NS3/4A protease with Ki of 2.6 and 2.0 nM for GT1a and 1b NS3-NS4A protease, respectively. |
| PC-60952 |
Deleobuvir
HCV NS5B inhibitor
|
Deleobuvir (BI-207127, BI207127) is a potent, selective HCV NS5B polymerase inhibitor with IC50 of 50 nM against GT-1 HCV polymerase activity. |
| PC-60429 |
MK-8876
HCV NS5B inhibitor
|
MK-8876 is a broadly acting non-nucleoside inhibitor of HCV NS5B polymerase with IC50 of 3 nM and 2 nM for GT1b and GT2a, respectively.. |
| PC-60428 |
GSK-2485852
HCV NS5B inhibitor
|
GSK-2485852 (GSK2485852, GSK5852) is a highly potent, selective HCV NS5B polymerase inhibitor with IC50 of 3.0 and 1.6 nM for HCV genotypes 1a and 1b in replicon assay, respectively. |
| PC-60427 |
BMS-929075
HCV NS5B inhibitor
|
A highly potent, selective, orally bioavailable HCV NS5B polymerase inhibitor with IC50 of 9, 4, and 18 nM for GT1a, GT1b, and GT1b-C316N mutant in HCV replicon assay, respectively. |
| PC-60425 |
GSK-625433
HCV NS5B inhibitor
|
GSK-625433 is highly potent, selective HCV NS5B polymerase inhibitor for treatment of HCV infection, inhibits the polymerase of both HCV genotypes 1a and 1b. |
| PC-60424 |
BMT-052
HCV NS5B inhibitor
|
BMT-052 is a second generation, orally biovailable pan-genotypic HCV NS5B polymerase inhibitor with EC50 of 1-10 nM. |
| PC-60309 |
Ruzasvir
HCV NS5A inhibitor
|
Ruzasvir (MK-8408) is a potent, pan-genotype HCV NS5A inhibitor with replicon EC90 of 0.003, 0.016, 0.067, 0.036, 0.007, and 0.007 nM for GT1a, GT1a L31V, GT1a Y93H, GT2b, GT3a, and Gt4a, respectively. |
