Catalog No.: PC-60953Not For Human Use, Lab Use Only.
Faldaprevir (BI-201335) is a potent, selective noncovalent competitive inhibitor of HCV NS3/4A protease with Ki of 2.6 and 2.0 nM for GT1a and 1b NS3-NS4A protease, respectively.
Faldaprevir (BI-201335) is a potent, selective noncovalent competitive inhibitor of HCV NS3/4A protease with Ki of 2.6 and 2.0 nM for GT1a and 1b NS3-NS4A protease, respectively.
Faldaprevir (BI-201335) also shows Ki of 2 to 230 nM for HCV GT2 to 6, potently inhibits HCV RNA replication in vitro of 6.5 and 3.1 nM in genotype 1a and 1b replicon assays, respectively.
Faldaprevir (BI-201335) possesses good ADME profile in vitro and pharmacokinetics in vivo.
