Cat. No. |
Product Name |
Information |
PC-42478 |
Danoprevir
HCV NS3/4A inhibitor
|
Danoprevir (ITMN-191, R-7227) is a potent, highly selective, orally available, peptidomimetic HCV NS3/4A protease inhibitor with IC50 of 0.2-0.4 nM (GT1a, 1b, 4, 5 and 6), 1.6 nM (GT2b). |
PC-42722 |
RO-9187
HCV NS5B inhibitor
|
RO-9187 is a potent HCV NS5B RNA polymerase inhibitor, inhibits HCV replication in the replicon system with IC50 of 171 nM. |
PC-42604 |
Daclatasvir
HCV NS5A inhibitor
|
Daclatasvir (BMS-790052) is a potent HCV NS5A inhibitor with EC50 of <50 pM against genotype 1 replicons. |
PC-42603 |
Daclatasvir dihydrochloride
HCV NS5A inhibitor
|
Daclatasvir (BMS-790052) dihydrochloride is a potent HCV NS5A inhibitor with EC50 of <50 pM against genotype 1 replicons. |
PC-45961 |
Lomibuvir
HCV NS5B inhibitor
|
Lomibuvir (VX-222, VCH-222) is a potent and selective, nonnucleoside inhibitor of HCV NS5B polymerase inhibitor with Kd of 17 nM. |
PC-42605 |
NM107
HCV NS5B inhibitor
|
NM107 (Valopicitabine) is a nucleoside inhibitor of HCV NS5B polymerase with EC50 of 1.23 uM against HCV 1b replicon cells. |
PC-42023 |
Peretinoin
|
Peretinoin (NIK333) is an orally available, synthetic retinoid with potential antineoplastic and chemopreventive activities. |
PC-42646 |
Tegobuvir
HCV NS5B inhibitor
|
Tegobuvir (GS-333126, GS-9190) is a nonnucleoside inhibitor of HCV NS5B polymerase that acts as a potent inhibitor of HCV genotype 1. |
PC-45985 |
Nucleoside-Analog-1
|
A 4′-azidocytidine analogue that shows anti-HCV activity.. |
PC-25230 |
Asunaprevir
HCV NS3 inhibitor
|
Asunaprevir (BMS-650032) is a potent and orally bioavailable hepatitis C virus (HCV) NS3 protease inhibitor with IC50 of 0.2-3.5 nM, also inhibits SARS-CoV-2 3CLpro activity. |
PC-25228 |
Grazoprevir
HCV NS3/4A inhibitor
|
Grazoprevir (MK-5172) is a potent, selective inhibitor of HCV NS3/4A protease with broad activity across genotypes and resistant variants, with Ki values of 0.01 nM (gt1b), 0.01 nM (gt1a), 0.08 nM (gt2a), 0.15 nM (gt2b), 0.90 nM (gt3a), respectively, also inhibits SARS-CoV-2 3CLpro activity. |
PC-24161 |
Netanasvir phosphate
HCV NS5A inhibitor
|
Netanasvir phosphate is a potent, selective fused bicyclic inhibitor of HCV NS5A. |