NM107 |CAS:20724-73-6 Probechem Biochemicals

Chemical Structure : NM107

CAS No.: 20724-73-6

NM107 (2'-C-Methylcytidine;NM-107;Valopicitabine)

Catalog No.: PC-42605Not For Human Use, Lab Use Only.

NM107 (Valopicitabine) is a nucleoside inhibitor of HCV NS5B polymerase with EC50 of 1.23 uM against HCV 1b replicon cells.

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Biological Activity

NM107 (Valopicitabine) is a nucleoside inhibitor of HCV NS5B polymerase with EC50 of 1.23 uM against HCV 1b replicon cells.
NM107 (Valopicitabine) is the active component of NM283.

Physicochemical Properties

M.Wt	257.2432
Formula	C10H15N3O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Cytidine, 2'-C-methyl-

References

1. Gardelli C, et al. J Med Chem. 2009 Sep 10;52(17):5394-407.

2. McCown MF, et al. Antimicrob Agents Chemother. 2008 May;52(5):1604-12.

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NM107 (2'-C-Methylcytidine;NM-107;Valopicitabine)

Biological Activity

Physicochemical Properties

References

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