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Chemical Structure : Tegobuvir
CAS No.: 1000787-75-6
Catalog No.: PC-42646Not For Human Use, Lab Use Only.
A nonnucleoside inhibitor of HCV NS5B polymerase that acts as a potent inhibitor of HCV genotype 1.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $400 | In stock | |
| 50 mg | $1200 | In stock |
Bulk size, bulk discount!
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A nonnucleoside inhibitor of HCV NS5B polymerase that acts as a potent inhibitor of HCV genotype 1; inhibits 1a (H77) and 1b (Con-1) replicons with EC50 of 13.8 nM and 0.8 nM respectively, and displays a loss in potency against 2a (JFH-1) virus with EC50 of 2.9 uM.
| M.Wt | 517.401 | |
| Formula | C25H14F7N5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
5H-Imidazo[4,5-c]pyridine, 5-[[6-[2,4-bis(trifluoromethyl)phenyl]-3-pyridazinyl]methyl]-2-(2-fluorophenyl)- |
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1. Shih IH, et al. Antimicrob Agents Chemother. 2011 Sep;55(9):4196-203.
2. Zeuzem S, et al. Hepatology. 2012 Mar;55(3):749-58.
3. Wong KA, et al. Virology. 2012 Jul 20;429(1):57-62.
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