Voxilaprevir |CAS:1535212-07-7 Probechem Biochemicals

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Chemical Structure : Voxilaprevir

CAS No.: 1535212-07-7

Voxilaprevir (GS-9857, GS9857)

Catalog No.: PC-61440Not For Human Use, Lab Use Only.

Voxilaprevir (GS-9857) is a potent HCV NS3/4A protease inhibitor that is used in combination with sofosbuvir and velpatasvir for treatment of HCV infection.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Voxilaprevir (GS-9857) is a potent HCV NS3/4A protease inhibitor that is used in combination with sofosbuvir and velpatasvir for treatment of HCV infection.

Physicochemical Properties

M.Wt	868.94
Formula	C40H52F4N6O9S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(33R,34S,35S,91R,92R,5S)-5-(tert-butyl)-N-((1R,2R)-2-(difluoromethyl)-1-(((1-methylcyclopropyl)sulfonyl)carbamoyl)cyclopropyl)-34-ethyl-14,14-difluoro-17-methoxy-4,7-dioxo-2,8-dioxa-6-aza-1(2,3)-quinoxalina-3(3,1)-pyrrolidina-9(1,2)-cyclopropanacyclotetradecaphane-35-carboxamide

References

1. Bourlière M, et al. N Engl J Med. 2017 Jun 1;376(22):2134-2146.

2. Gane EJ, et al. Gastroenterology. 2016 Nov;151(5):902-909.

3. Lawitz E, et al. Gastroenterology. 2016 Nov;151(5):893-901.e1.

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Voxilaprevir (GS-9857, GS9857)

Biological Activity

Physicochemical Properties

References

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