IDX17119 | HCV NS5B inhibitor | Probechem Biochemicals

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Chemical Structure : IDX17119

IDX17119 (IDX-17119)

Catalog No.: PC-62784Not For Human Use, Lab Use Only.

IDX17119 is a potent, non-nucleoside, HCV NS5B RdRp inhibitor with IC50 of 0.4 nM in replicon luciferase assays.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

IDX17119 is a potent, non-nucleoside, HCV NS5B RdRp inhibitor with IC50 of 0.4 nM in replicon luciferase assays.
IDX17119 shows activity against broad genotype profile: IC50= 0.0099 uM, 0.2538 uM, 0.1809 uM and 0.0257 uM on genotypes 1b, 2a, 3a and 4a, respectively.

Physicochemical Properties

M.Wt	531.513
Formula	C26H26N7O4P
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-(7-amino-5-methylpyrazolo[1,5-a]pyrimidin-2-yl)phenyl)-3-(((2,4-dimethylphenyl)(methoxy)phosphoryl)amino)-1H-pyrazole-4-carboxylic acid

References

1. Pierra Rouvière C, et al. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4536-41.

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IDX17119 (IDX-17119)

Biological Activity

Physicochemical Properties

References

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