Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
EN | CN

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Antibiotics and Antivirals-HCV-Anguizole
Anguizole

Chemical Structure : Anguizole

CAS No.: 442666-98-0

Add to Favorites

Anguizole (HCV NS4B inhibitor)

Catalog No.: PC-43491Not For Human Use, Lab Use Only.

Anguizole is a HCV NS4B inhibitor targeting second amphipathic helix of NS4B (NS4B-AH2), blocks genotype 1b HCV replication with EC50 of 310 nM.

Packing Price Stock Quantity
10 mg $148 In stock
25 mg $258 In stock
50 mg $428 In stock
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Anguizole is a HCV NS4B inhibitor targeting second amphipathic helix of NS4B (NS4B-AH2), blocks genotype 1b HCV replication with EC50 of 310 nM.
Anguizole disrupts NS4B-AH2-mediated biological functions of NS4B, NS4B's dimerization/multimerization, its proper subcellular localization, as well as its interaction with NS5A.

Physicochemical Properties

M.Wt 408.81
Formula C17H11ClF2N4O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Pyrazolo[1,5-a]pyrimidine-2-carboxamide, 7-(chlorodifluoromethyl)-5-(2-furanyl)-N-(2-thienylmethyl)-

References

1. Choi M, et al. Virus Genes. 2013 Dec;47(3):395-407.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: