Chemical Structure : Anguizole
Catalog No.: PC-43491Not For Human Use, Lab Use Only.
Anguizole is a HCV NS4B inhibitor targeting second amphipathic helix of NS4B (NS4B-AH2), blocks genotype 1b HCV replication with EC50 of 310 nM.
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Anguizole is a HCV NS4B inhibitor targeting second amphipathic helix of NS4B (NS4B-AH2), blocks genotype 1b HCV replication with EC50 of 310 nM; disrupts NS4B-AH2-mediated biological functions of NS4B, NS4B's dimerization/multimerization, its proper subcellular localization, as well as its interaction with NS5A.
M.Wt | ||
Formula | C17H11ClF2N4O2S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Choi M, et al. Virus Genes. 2013 Dec;47(3):395-407.
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