Dichlorcyclizine | HCV entry inhibitor

Chemical Structure : Dichlorcyclizine

Dichlorcyclizine (DCCZ)

Catalog No.: PC-72892Not For Human Use, Lab Use Only.

Dichlorcyclizine (DCCZ) is a potent, small molecule HCV fusion inhibitor, also inhibits SARS-CoV and SARS-CoV-2 S-mediated infection with EC50 of 9.92 and 4.53 uM, respectively.

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Biological Activity

Dichlorcyclizine (DCCZ) is a potent, small molecule HCV fusion inhibitor, also inhibits SARS-CoV and SARS-CoV-2 S-mediated infection in MA104 cells with EC50 of 9.92 and 4.53 uM, respectively.

Physicochemical Properties

M.Wt	349.299
Formula	C19H22Cl2N2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(bis(4-chlorophenyl)methyl)-4-ethylpiperazine

References

1. Christopher D Ma, et al. Nat Microbiol. 2020 Dec;5(12):1532-1541.

2. Park SB, et al. mBio. 2022 Jan 11;13(1):e0323821.

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Dichlorcyclizine (DCCZ)

Biological Activity

Physicochemical Properties

References

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