Chemical Structure : Ledipasvir
CAS No.:
1256388-51-8
Ledipasvir
(GS-5885, GS5885)
Catalog No. : PC-21354Not For Human Use, Lab Use Only.
Ledipasvir (GS-5885) is a potent, selective and oral HCV NS5A inhibitor with EC50 of 31 pM and 4 pM against GT1a and GT1b, respectively.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-2135401
Biological Activity
Ledipasvir (GS-5885) is a potent, selective and oral HCV NS5A inhibitor with EC50 of 31 pM and 4 pM against GT1a and GT1b, respectively.
Physicochemical Properties
M.Wt
889.02
Formula
C49H54F2N8O6
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Methyl ((S)-1-((S)-6-(5-(9,9-difluoro-7-(2-((1R,3S,4S)-2-((methoxycarbonyl)-L-valyl)-2-azabicyclo[2.2.1]heptan-3-yl)-1H-benzo[d]imidazol-6-yl)-9H-fluoren-2-yl)-1H-imidazol-2-yl)-5-azaspiro[2.4]heptan-5-yl)-3-methyl-1-oxobutan-2-yl)carbamate
References
1. Link JO, et al. J Med Chem. 2014 Mar 13;57(5):2033-46.
2. Wong KA, et al. Antimicrob Agents Chemother. 2013 Dec;57(12):6333-40.
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