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Request The Product List ofDeubiquitinase (DUB) Deubiquitinase (DUB)

Cat. No. Product Name Information
PC-21796

YCH2823

USP7 inhibitor

YCH2823 is a potent, selective USP7 inhibitor with IC50 of 49.6 nM, ITC Kd of 117 nM.
PC-21610

HY041004

JOSD2 inhibitor

HY041004 is the first small molecule inhibitor of deubiquitinase Josephin Domain-containing protein 2 (JOSD2) with IC50 of 0.26 uM for JOSD2 catalytic activity inhibition.
PC-21573

NCI677397

USP24 inhibitor

NCI677397 is a specific small molecule inhibitor of USP24, inhibits chemotherapy-induced drug resistance in vitro and in vivo.
PC-21519

MS102

USP2 inhibitor

MS102 is a small molecule, orally available USP2 inhibitor with IC50 of 5.46 uM, induces transient degradation of ACE2 protein and inhibits ACE2-dependent coronavirus infection.
PC-21098

LN5P45

OTUB2 inhibitor

LN5P45 is a selective, covalent, irreversible inhibitor of ubiquitin thioesterase OTUB2 with IC50 of 2.3 uM, strongly induces monoubiquitination of OTUB2 on Lys31.
PC-20480

Neutral Red

USP4 inhibitor

Neutral Red is a nitrogenous pH-indicator that can stains lysosomes red, also is a selective, uncompetitive USP4 inhibitor with IC50 of 50 uM.
PC-20472

IU1-206

USP14 inhibitor

IU1-206 is a IU1 derivative with more potent activity against USP14, 10-fold more potent than IU1 and is comparable to the IU1-47.
PC-20403

PR-619

DUBs inhibitor

PR-619 (PR619) is a broad-spectrum, reversible deubiquitinating enzymes (DUBs) inhibitor with IC50 of 3.93 uM-8.87 uM.
PC-20202

HBX41108

USP7 inhibitor

HBX41108 is a specific small-molecule inhibitor of USP7/HAUSP ubiquitin protease with IC50 of 424 nM for inhibition of Ub-AMC hydrolysis by USP7.
PC-20190

USP14 inhibitor 3

USP14 inhibitor

USP14-IN-3 is a specific small molecule USP14 inhibitor with IC50 of <0.5 uM.
PC-20189

USP14 inhibitor 2

USP14 inhibitor

USP14-IN-2 is a specific small molecule USP14 inhibitor with IC50 of <0.5 uM.
PC-20186

USP14 inhibitor 1

USP14 inhibitor

USP14-IN-1 is a specific small molecule USP14 inhibitor with IC50 of 0.5 uM.

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