| Cat. No. |
Product Name |
Information |
| PC-22877 |
YCH3124
USP7 inhibitor
|
YCH3124 is a potent, selective USP7 inhibitor with IC50 of 41.9 nM and Kd of 156 nM, exhibits minimal inhibition against other USPs, including USP1, USP4, USP8, USP9X, USP15, and USP25. |
| PC-22864 |
USP1 inhibitor C527
USP1 inhibitor
|
USP1 inhibitor C527 is a specific small-molecule inhibitor of USP1 blocking the deubiquitinating enzyme activity of USP1 with IC50 of 0.88 uM (USP/UAF1 complex). |
| PC-22863 |
Zerumbone
TAGLN/USP1 inhibitor
|
Zerumbone is a natural cyclic sesquiterpene and can be isolated from Zingiber zerumbet with anti-proliferative, anti-inflammation, anti-cancer, anti-bacterial and anti-mutagenic activity, binds to transgelin (TAGLN) and reduces the retention of USP1 in the cytoplasm and the degradation of ZEB1 ubiquitination. |
| PC-22320 |
Compound 7695-0983
FAT10 inhibitor
|
Compound 7695-0983 is a small molecule inhibitor of HLA-F locus-adjacent transcript 10 (FAT10), inhibits the expression of FAT10, inhibits NEDD4-PTEN/AKT axis-mediated autophagy. |
| PC-22319 |
IMP-2586
USP30 inhibitor
|
IMP-2586 is a potent, selective ubiquitin-specific protease 30 (USP30) inhibitor with IC50 of 16.3 nM, binding Ki of 5.6 nM. |
| PC-22318 |
IMP-2587
USP30 inhibitor
|
IMP-2587 is a potent, selective ubiquitin-specific protease 30 (USP30) inhibitor with IC50 of 12.6 nM, binding Ki of 42.7 nM. |
| PC-22313 |
USP10 inhibitor D1
USP10 inhibitor
|
USP10 inhibitor D1 is a potent, selective small molecule ubiquitin-specific protease 10 (USP10) inhibitor with IC50 of 7.2 uM, KD of 5.24 uM in microscale thermophoresis (MST)-based binding assay. |
| PC-22261 |
CT1113
USP28 inhibitor
|
CT1113 is a potent, selective small molecule USP25/USP28 inhibitor with IC50 of 26.1 nM/3.9 nM, respectively. |
| PC-22260 |
FX1-5303
USP7 inhibitor
|
FX1-5303 is a highly potent, specific ubiquitin-specific protease 7 (USP7) inhibitor with biochemical IC50 of 0.29 nM. |
| PC-22183 |
Vialinin A
USP4/USP5 inhibitor
|
Vialinin A (Terrestrin A) is a p-terphenyl compound with antioxidant properties, inhibits the peptidase activity of USP5/IsoT with IC50 of 5.9 uM, also inhibits the enzymatic activities of USP4 with IC50 of 1.5 uM. |
| PC-21919 |
LLK203
USP2/USP8 inhibitor
|
LLK203 is a potent, dual-targeting USP2/USP8 inhibitor with IC50 of 0.89/0.52 uM, potently inhibits cell proliferation of MCF-7 breast cancer cells with IC50 of 3.4 uM. |
| PC-21918 |
PCR-6236
USP2/USP8 inhibitor
|
PCR-6236 is a potent dual-targeting USP2/USP8 inhibitor with IC50 of <0.1/0.8 uM, respectively. |
