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Request The Product List ofDeubiquitinase (DUB) Deubiquitinase (DUB)

Cat. No. Product Name Information
PC-22183

Vialinin A

USP4/USP5 inhibitor

Vialinin A (Terrestrin A) is a p-terphenyl compound with antioxidant properties, inhibits the peptidase activity of USP5/IsoT with IC50 of 5.9 uM, also inhibits the enzymatic activities of USP4 with IC50 of 1.5 uM.
PC-21919

LLK203

USP2/USP8 inhibitor

LLK203 is a potent, dual-targeting USP2/USP8 inhibitor with IC50 of 0.89/0.52 uM, potently inhibits cell proliferation of MCF-7 breast cancer cells with IC50 of 3.4 uM.
PC-21918

PCR-6236

USP2/USP8 inhibitor

PCR-6236 is a potent dual-targeting USP2/USP8 inhibitor with IC50 of <0.1/0.8 uM, respectively.
PC-21881

P22077

USP7/USP47 inhibitor

P22077 is a selective cell-permeable ubiquitin-specific protease 7 (USP7) inhibitor with IC50 of 8.01 uM, also inhibits USP47 with IC50 of 8.47 uM.
PC-21561

P5091

USP7 inhibitor

P5091 is a potent, specific inhibitor of ubiquitin-specific protease 7 (USP7) with IC50 of 4.2 uM, does not inhibit other DUBs or other families of cysteine proteases (EC50> 100 uM).
PC-21559

USP3 inhibitor 59

USP3 inhibitor

USP3 inhibitor 59 is a relatively specific small molecule chemical handle with SPR value of 14 uM, binds to zinc-finger ubiquitin binding domain (ZnF-UBD).
PC-21498

IMP-2373

DUB CNPy Probe

IMP-2373 is a highly targeted cyanopyrrolidine (CNPy) probe for pan-DUB to monitor DUB activity in physiologically relevant live cells.
PC-21351

MTX115325

USP30 inhibitor

MTX115325 is a potent, selective, brain-penetrant USP30 inhibitor with IC50 of 12 nM in biochemical fluorescence polarization assays.
PC-20938

OTUDin3

OTUD3 inhibitor

OTUDin3 (OTUD3 inhibitor) is a specific, small molecule inhibitor of deubiquitylase OTUD3, binds to OTUD3 (KD=0.32 uM) and inhibits the deubiquitinating activity of OTUD3 by interfering with Ub binding to OTUD3.
PC-20796

BK50118-C

USP13 inhibitor

BK50118-C is a potent small molecule inhibitor of ubiquitin-specific protease-13 (USP13) with IC50 of 0.42 nM.
PC-20656

b-AP15

USP14 inhibitor

b-AP15 is a specific inhibitor of ubiquitin-specific-processing protease 14 (USP14) and ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCHL5), inhibits DUB activity in purified 19S proteasomes with IC50 of 2.1 uM.
PC-20592

USP28 inhibitor 19

USP28 inhibitor

USP28 inhibitor 19 is a potent, selective USP28 inhibitor with IC50 of 1.1 uM, does not inhibit USP7 and LSD1 (IC50>100 uM).

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