| Cat. No. |
Product Name |
Information |
| PC-27903 |
USP15-IN-1
USP15 inhibitor
|
USP15-IN-1 is a small molecule ubiquitin-specific peptidase 15 (USP15) inhibitor with IC50 of 3.76 uM, has USP15 inhibitory activity and anticancer activity. |
| PC-27899 |
USP20 inhibitor C2
USP20 inhibitor
|
USP20 inhibitor C2 is a small molecule Ubiquitin-Specific Protease 20 (USP20) inhibitor with IC50 of 13.55 uM (300 nM Ub-Rho110 as substrate), directly deubiquitinates and stabilizes fatty acid synthase (FASN), suppresses de novo lipogenesis (DNL) to alleviate MASLD. |
| PC-27640 |
CT1170
OTUD5 inhibitor
|
CT1170 is a potent, small molecule inhibitor of deubiquitinase OTUD5 with IC50 of 147.6 nM in DUB assays, enhances the ubiquitination modification on STAT1 and STAT2. |
| PC-26962 |
DC-U43-10
USP8 inhibitor
|
DC-U43-10 (USP8-IN-1) is a specific small molecule USP8 inhibitor with IC50 of 2.6 uM, exhibits 10-fold selectivity against USP7. |
| PC-26913 |
TH-407a
USP15 inhibitor
|
TH-407a is a potent and selective, reversible, non-competitive inhibitor of ubiquitin-specific peptidase 15 (USP15) with IC50 of 0.76 uM. |
| PC-26593 |
Huib32
USP32 inhibitor
|
Huib32 is a potent, selective small-molecule inhibitor of USP32 with IC50 of 21.2 nM, high selectivity over other closely related deubiquitinating enzymes (DUBs). |
| PC-26500 |
WEHI-092
USP9X inhibitor
|
WEHI-092 is a potent and selective inhibitor of USP9X with IC50 of 254 nM, directly binds to USP9X catalytic domain with SPR KD of 1 uM, does not inhibit USP24 and other DUBs. |
| PC-26283 |
UC495
OTULIN inhibitor
|
UC495 is a specific small molecule inhibitor of deubiquitinase OTULIN, interacts with the OTULIN deubiquitinase binding pocket. |
| PC-25948 |
WW-104
USP10 inhibitor
|
WW-104 is a specific small molecule USP10 inhibitor with IC50 of 16.75 uM and strong binding affinity with SPR Kd of 237 nM, shows no detectable inhibitory activity against USP7. |
| PC-25852 |
BB07CA902
mUSP18 inhibitor
|
BB07CA902 is a potent, specific, covalent inhibitor of interferon-stimulated gene 15 (ISG15) protease murine USP18 (mUSP18) with IC50 of 35 nM, effectively increases ISGylation levels in cells by inhibiting mUSP18 activity. |
| PC-25570 |
OAT-4828
USP7 inhibitor
|
OAT-4828 is a potent, and selective USP7 inhibitor with IC50 of 22 nM in enzymatic assay and 33 nM in reporter assay (Ub-CHOP reporter system). |
| PC-25548 |
WCY-8-67
USP5 inhibitor
|
WCY-8-67 is a potent, selective inhibitor of deubiquitinating enzyme (DUB) USP5 with IC50 of 0.33 uM and SPR Kd of 5.73 uM, inhibits the growth of t(8;21) AML cells. |
