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Request The Product List ofDeubiquitinase (DUB) Deubiquitinase (DUB)

Cat. No. Product Name Information
PC-22953

MS5105

OTUB1 ligand

MS5105 is a small molecule OTUB1-covalent ligand, display improved effectiveness in covalently modifying OTUB1 compared with EN523, is useful for DUBTAC design.
PC-22885

USP7 inhibitor X36

USP7 inhibitor

USP7 inhibitor X36 is a potent, selective and orally active USP7 inhibitor with IC50 of 64.5 nM, shows no activity against a panel of 9 DUBs including USP47.
PC-22878

FLX4

USP7 inhibitor

FLX4 is a potent, selective and allosteric inhibitor of USP7 with IC50 of <1 uM.
PC-22877

YCH3124

USP7 inhibitor

YCH3124 is a potent, selective USP7 inhibitor with IC50 of 41.9 nM and Kd of 156 nM, exhibits minimal inhibition against other USPs, including USP1, USP4, USP8, USP9X, USP15, and USP25.
PC-22864

USP1 inhibitor C527

USP1 inhibitor

USP1 inhibitor C527 is a specific small-molecule inhibitor of USP1 blocking the deubiquitinating enzyme activity of USP1 with IC50 of 0.88 uM (USP/UAF1 complex).
PC-22863

Zerumbone

TAGLN/USP1 inhibitor

Zerumbone is a natural cyclic sesquiterpene and can be isolated from Zingiber zerumbet with anti-proliferative, anti-inflammation, anti-cancer, anti-bacterial and anti-mutagenic activity, binds to transgelin (TAGLN) and reduces the retention of USP1 in the cytoplasm and the degradation of ZEB1 ubiquitination.
PC-22320

Compound 7695-0983

FAT10 inhibitor

Compound 7695-0983 is a small molecule inhibitor of HLA-F locus-adjacent transcript 10 (FAT10), inhibits the expression of FAT10, inhibits NEDD4-PTEN/AKT axis-mediated autophagy.
PC-22319

IMP-2586

USP30 inhibitor

IMP-2586 is a potent, selective ubiquitin-specific protease 30 (USP30) inhibitor with IC50 of 16.3 nM, binding Ki of 5.6 nM.
PC-22318

IMP-2587

USP30 inhibitor

IMP-2587 is a potent, selective ubiquitin-specific protease 30 (USP30) inhibitor with IC50 of 12.6 nM, binding Ki of 42.7 nM.
PC-22313

USP10 inhibitor D1

USP10 inhibitor

USP10 inhibitor D1 is a potent, selective small molecule ubiquitin-specific protease 10 (USP10) inhibitor with IC50 of 7.2 uM, KD of 5.24 uM in microscale thermophoresis (MST)-based binding assay.
PC-22261

CT1113

USP28 inhibitor

CT1113 is a potent, selective small molecule USP25/USP28 inhibitor with IC50 of 26.1 nM/3.9 nM, respectively.
PC-22260

FX1-5303

USP7 inhibitor

FX1-5303 is a highly potent, specific ubiquitin-specific protease 7 (USP7) inhibitor with biochemical IC50 of 0.29 nM.

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