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Request The Product List ofDeubiquitinase (DUB) Deubiquitinase (DUB)

Cat. No. Product Name Information
PC-43050

VLX1570

DUBs inhibitor

VLX1570 is a small molecule b-AP15 analog that fucttion as proteasome deubiquitinase inhibitor with IC50 of 10 uM, interacts at the active sites of the proteasome DUBs USP14 and UCHL5.
PC-62856

BRD0476

USP9X inhibitor

BRD 0476 (ML187) is a selective, moderate inhibitor of ubiquitin-specific peptidase 9X (USP9X), inhibits pancreatic β-cell apoptosis that inhibits IFN-γ-induced JAK2 and STAT1 signaling to promote β-cell survival.
PC-62623

IU1-47

USP14 inhibitor

IU1-47 is a potent, selective small-molecule inhibitor of USP14 with IC50 of 0.6 uM, shows 10-fold more potent over IU1 and retains specificity for USP14.
PC-62574

P217564

USP7 inhibitor

P 217564 is a potent, selective, irreversible second generation inhibitor of USP7 with IC50 of 0.48 uM, with similar potency against USP47 and no significant activity aginst other DUBs.
PC-62449

HBX 28258

USP7 inhibitor

HBX 28258 is a potent, selective USP7 inhibitor with IC50 of 22.6 uM, exhibits high selectivity over other USP members, such as USP8, USP5, USP2, and USP20 (IC50 >200 uM), and no activity against UCH-L1, UCH-L3 and SENP1.
PC-62189

Spautin-1

Autophagy inhibitor

Spautin-1 is a potent, small molecule inhibitor of autophagy with IC50 of 0.74 uM, inhibits USP10 and USP13 with IC50 of 0.6-0.7 uM, but not USP14.
PC-61936

LDN 91946

UCHL1 inhibitor

LDN 91946 is a selective, uncompetitive ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor with Ki of 2.8 uM, exhibits no activity against other cysteine hydrolase (UCH-L3, TGase 2, papain and caspase-3).
PC-61935

USP7i-1

USP7 inhibitor

USP7i-1 (USP7-IN-1) is a potent, selective USP7 inhibitor with IC50 of 77 uM.
PC-61934

USP10-IN-3

USP10 inhibitor

USP10-IN-3 is a HBX19818 analog, potent and selective USP10 inhibitor, but does not inhibit USP7 (IC50>100 uM).
PC-61933

USP10-IN-9

USP10 inhibitor

USP10-IN-9 is a HBX19818 analog, selective USP10 inhibitor with IC50 similar to HBX19818, but does not inhibit USP7 (IC50>100 uM)..
PC-61702

TCID

UCHL3 inhibitor

TCID is a selective ubiquitin C-terminal hydrolase-L3 (UCH-L3) inhibitor with IC50 of 0.6 uM, displays >100-fold selectivity over UCH-L1.
PC-61626

BC-1471

STAMBP inhibitor

BC-1471 is a selective, small-molecule deubiquitinase STAM-binding protein (STAMBP) inhibitor (IC50=0.33 uM) that interrupts STAMBP-Ub-NALP7 interaction.

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