Chemical Structure : MF-094
CAS No.: 2241025-68-1
Catalog No.: PC-35263Not For Human Use, Lab Use Only.
MF-094 (MF094) is a potent, highly selective inhibitor of ubiquitin specific protease 30 (USP30) with IC50 of 0.12 uM, demonstrates <30% inhibitory activity for a panel of 22 USPs assays at 10 uM.
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MF-094 (MF094) is a potent, highly selective inhibitor of ubiquitin specific protease 30 (USP30) with IC50 of 0.12 uM, demonstrates <30% inhibitory activity for a panel of 22 USPs assays at 10 uM.
MF-094 increases protein ubiquitination and accelerates mitophagy.
M.Wt | 535.703 | |
Formula | C30H37N3O4S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(S)-N-(1-((5-(N-(tert-butyl)sulfamoyl)naphthalen-1-yl)amino)-1-oxo-3-phenylpropan-2-yl)cyclohexanecarboxamide |
1. Kluge AF, et al. Bioorg Med Chem Lett. 2018 May 8. pii: S0960-894X(18)30402-5.
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