NSC112200 |CAS:28293-38-1 Probechem Biochemicals

Chemical Structure : NSC112200

NSC112200 (NSC 112200)

Catalog No.: PC-63454Not For Human Use, Lab Use Only.

NSC112200 is a chemical inhibitor of the EZH2 deubiquitinase ZRANB1 (at 10 uM), destabilizes EZH2, promotes proteasomal degradation of EZH2 and inhibits the viability of TNBC cells.

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Biological Activity

NSC112200 is a chemical inhibitor of the EZH2 deubiquitinase ZRANB1 (at 10 uM), destabilizes EZH2, promotes proteasomal degradation of EZH2 and inhibits the viability of TNBC cells.
0NSC112200 is a mixture of 2,5-dibromo-3,6-dimethyl-1,4- benzenediol and 2,5-dibromo-3,6-dimethyl-1,4-benzoquinone.

Physicochemical Properties

M.Wt	293.942
Formula	C8H6Br2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2,5-Dibromo-3,6-dimethyl-2,5-cyclohexadiene-1,4-dione

References

1. Zhang P, et al. Cell Rep. 2018 Apr 17;23(3):823-837.

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NSC112200 (NSC 112200)

Biological Activity

Physicochemical Properties

References

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