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IU1-248

Chemical Structure : IU1-248

CAS No.: 2307472-03-1

IU1-248 (USP14 inhibitor IU1-248)

Catalog No.: PC-35682Not For Human Use, Lab Use Only.

IU1-248 (USP14 inhibitor IU1-248) is a potent, selective USP14 inhibitor with IC50 of 0.83 uM, IU1-248 is an IU1 derivative that is 10-fold more potent than IU1.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

IU1-248 (USP14 inhibitor IU1-248) is a potent, selective USP14 inhibitor with IC50 of 0.83 uM, IU1-248 is an IU1 derivative that is 10-fold more potent than IU1.
IU1-248 exhibits 25-fold selectivity over USP5 (IsoT).

Physicochemical Properties

M.Wt 337.423
Formula C20H23N3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(3-(2-(4-hydroxypiperidin-1-yl)acetyl)-2,5-dimethyl-1H-pyrrol-1-yl)benzonitrile

References

1. Wang Y, et al. Cell Res. 2018 Sep 25. doi: 10.1038/s41422-018-0091-x.

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