IU1-248 | Probechem Biochemicals

Chemical Structure : IU1-248

CAS No.: 2307472-03-1

IU1-248 (USP14 inhibitor IU1-248)

Catalog No.: PC-35682Not For Human Use, Lab Use Only.

IU1-248 (USP14 inhibitor IU1-248) is a potent, selective USP14 inhibitor with IC50 of 0.83 uM, IU1-248 is an IU1 derivative that is 10-fold more potent than IU1.

Packing	Price	Stock
5 mg	$198	In stock
10 mg	$328	In stock
25 mg	$558	In stock
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Biological Activity

IU1-248 (USP14 inhibitor IU1-248) is a potent, selective USP14 inhibitor with IC50 of 0.83 uM, IU1-248 is an IU1 derivative that is 10-fold more potent than IU1.
IU1-248 exhibits 25-fold selectivity over USP5 (IsoT).

Physicochemical Properties

M.Wt	337.423
Formula	C20H23N3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(3-(2-(4-hydroxypiperidin-1-yl)acetyl)-2,5-dimethyl-1H-pyrrol-1-yl)benzonitrile

References

1. Wang Y, et al. Cell Res. 2018 Sep 25. doi: 10.1038/s41422-018-0091-x.

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IU1-248 (USP14 inhibitor IU1-248)

Biological Activity

Physicochemical Properties

References

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