Catalog No.: PC-62856Not For Human Use, Lab Use Only.
BRD 0476 (ML187) is a selective, moderate inhibitor of ubiquitin-specific peptidase 9X (USP9X), inhibits pancreatic β-cell apoptosis that inhibits IFN-γ-induced JAK2 and STAT1 signaling to promote β-cell survival.
BRD 0476 (ML187) is a selective, moderate inhibitor of ubiquitin-specific peptidase 9X (USP9X), inhibits pancreatic β-cell apoptosis that inhibits IFN-γ-induced JAK2 and STAT1 signaling to promote β-cell survival.
BRD 0476 does not has kinase inhibitory activity, and no effect no effect on JAK1, JAK2, or JAK3 activities.
The deubiquitinase ubiquitin-specific peptidase 9X (USP9X) is an intracellular target of BRD0476.
