| Cat. No. |
Product Name |
Information |
| PC-62623 |
IU1-47
USP14 inhibitor
|
IU1-47 is a potent, selective small-molecule inhibitor of USP14 with IC50 of 0.6 uM, shows 10-fold more potent over IU1 and retains specificity for USP14. |
| PC-62574 |
P217564
USP7 inhibitor
|
P 217564 is a potent, selective, irreversible second generation inhibitor of USP7 with IC50 of 0.48 uM, with similar potency against USP47 and no significant activity aginst other DUBs. |
| PC-62449 |
HBX 28258
USP7 inhibitor
|
HBX 28258 is a potent, selective USP7 inhibitor with IC50 of 22.6 uM, exhibits high selectivity over other USP members, such as USP8, USP5, USP2, and USP20 (IC50 >200 uM), and no activity against UCH-L1, UCH-L3 and SENP1. |
| PC-62189 |
Spautin-1
Autophagy inhibitor, USP10/USP13 inhibitor
|
Spautin-1 is a potent, small molecule inhibitor of autophagy with IC50 of 0.74 uM, inhibits USP10 and USP13 with IC50 of 0.6-0.7 uM, but not USP14. |
| PC-61936 |
LDN-91946
UCHL1 inhibitor
|
LDN-91946 is a selective, uncompetitive ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor with Ki of 2.8 uM, exhibits no activity against other cysteine hydrolase (UCH-L3, TGase 2, papain and caspase-3). |
| PC-61935 |
USP7i-1
USP7 inhibitor
|
USP7i-1 (USP7-IN-1) is a potent, selective USP7 inhibitor with IC50 of 77 uM. |
| PC-61934 |
USP10-IN-3
USP10 inhibitor
|
USP10-IN-3 is a HBX19818 analog, potent and selective USP10 inhibitor, but does not inhibit USP7 (IC50>100 uM). |
| PC-61933 |
USP10-IN-9
USP10 inhibitor
|
USP10-IN-9 is a HBX19818 analog, selective USP10 inhibitor with IC50 similar to HBX19818, but does not inhibit USP7 (IC50>100 uM).. |
| PC-61702 |
TCID
UCHL3 inhibitor
|
TCID is a selective ubiquitin C-terminal hydrolase-L3 (UCH-L3) inhibitor with IC50 of 0.6 uM, displays >100-fold selectivity over UCH-L1. |
| PC-61626 |
BC-1471
STAMBP inhibitor
|
BC-1471 is a selective, small-molecule deubiquitinase STAM-binding protein (STAMBP) inhibitor (IC50=0.33 uM) that interrupts STAMBP-Ub-NALP7 interaction. |
| PC-61303 |
EOAI3402143
Usp9x/Usp24 inhibitor
|
EOAI3402143 (Deubiquitinase inhibitor G9, EOAI 3402143) is a novel covalent deubiquitinase Usp9x/Usp24 inhibitor (IC50=1.6 uM). |
| PC-61234 |
IU-1
USP14 inhibitor
|
IU-1 (USP14 inhibitor IU1) is a specific, small molecule inhibitor of deubiquitinating enzyme USP14 with IC50 of 4-5 uM. |
