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Chemical Structure : Ubiquitin Isopeptidase-IN-G5
CAS No.: 108477-18-5
Catalog No.: PC-42241Not For Human Use, Lab Use Only.
Ubiquitin Isopeptidase-IN-G5 (NSC 144303) is a small molecule inhibitor of ubiquitin-proteasome system by inhibiting the ubiquitin isopeptidases.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $118 | In stock | |
| 25 mg | $188 | In stock | |
| 50 mg | $318 | In stock | |
| 100 mg | $528 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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Ubiquitin Isopeptidase-IN-G5 (NSC 144303) is a small molecule inhibitor of ubiquitin-proteasome system by inhibiting the ubiquitin isopeptidases.
Ubiquitin Isopeptidase-IN-G5 (NSC 144303) induce a unique apoptotic pathway, which includes a Bcl-2-dependent but apoptosome-independent mitochondrial pathway with up-regulation of the BH3-only protein Noxa, stabilization of the IAP antagonist Smac, but also the involvement of the death receptor pathway.
| M.Wt | 414.3887 | |
| Formula | C19H14N2O7S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 31 mg/mL |
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| Chemical Name/SMILES |
4H-Thiopyran-4-one, tetrahydro-3,5-bis[(4-nitrophenyl)methylene]-, 1,1-dioxide |
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1. Aleo E, et al. Cancer Res. 2006 Sep 15;66(18):9235-44.
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