| Cat. No. |
Product Name |
Information |
| PC-72835 |
EN523
OTUB1 ligand
|
EN523 (EN-523) is a small molecule covalent ligand that targets a non-catalytic allosteric cysteine C23 in the K48-ubiquitin-specific deubiquitinase OTUB1, OTUB1 recruiter component of DUBTAC NJH-2-057. |
| PC-72699 |
MT16-001
UCHL1 inhibitor
|
MT16-001 is a selective, covalent inhibitor of deubiquitinating enzyme UCHL1 with IC50 of 580 nM, no inhibitory effect against UCHL3 (IC50>30 uM). |
| PC-72535 |
HBX-90659
USP8 inhibitor
|
HBX-90659 (compound 22 e) is a potent, selective USP8 inhibitor with IC50 of 0.28 uM, with no effect on USP7 (IC50 of >100 uM). |
| PC-72534 |
USP8 inhibitor RA-9
USP8 inhibitor
|
USP8 inhibitor RA-9 is a small molecule USP8 inhibitor. |
| PC-72414 |
USP5 inhibitor 64
USP5 inhibitor
|
USP5 inhibitor 64 is a selective chemical probe (inhibitor) against USP5 deubiquitinase, binds to the USP5 ZnF-UBD (zinc-finger ubiquitin binding domain) with KD of 2.8 uM. |
| PC-72297 |
iBAP
BAP1 inhibitor
|
iBAP (BAP1 inhibitor I) is a first-in-class inhibitor of the catalytic activity of BAP1 histone H2A deubiquitinase complex with IC50 of 0.5-1 uM in vitro, |
| PC-72296 |
iBAP-II
BAP1 inhibitor
|
iBAP-II (BAP1 inhibitor II) is a next-generation, specific small molecule inhibitor of BAP1 histone H2A deubiquitinase activity with IC50 of <0.1 ug/mL. |
| PC-72255 |
USP30 inhibitor Q14 peptide
USP30 inhibitor
|
USP30 inhibitor Q14 peptide is a potent peptide inhibitor of USP30 with IC50 of 57.2 nM, inhibits the deubiquitinating activities of USP30, increases mitophagy. |
| PC-72254 |
USP30Inh-1
USP30 inhibitor
|
USP30Inh-1 is a potent, selective small molecule USP30 inhibitor with IC50 of 15-30 nM (inhibition of USP30-mediated cleavage of Ub-Rho110). |
| PC-72253 |
FT385
USP30 inhibitor
|
FT385 (FT3967385) is a potent, selective USP30 inhibitor with biochemical IC50 of 1.5 nM. |
| PC-72252 |
USP30 inhibitor Compound 39
USP30 inhibitor
|
USP30 inhibitor Compound 39 (CMPD-39) is a highly selective inhibitor of USP30 with IC50 of 20 nM in an in vitro assay of enzyme activity, >100-fold selectivity over other DUBs. |
| PC-72221 |
MT16-205
UCHL1 inhibitor
|
MT16-205 (MT 16-205) is a potent, selective, covalent UCHL1 inhibitor with IC50 of 600 nM, no inhibition agianst UCHL3 (IC50>10 uM). |
