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Chemical Structure : USP inhibitor 1
Catalog No.: PC-73353Not For Human Use, Lab Use Only.
USP inhibitor 1 is an irreversible USP inhibitor with submicromolar IC50 of USP4 and its phylogenetic relative USP11, also functionally inhibits USP33, leading to CP110 instability and synergy with ATR inhibition.
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USP inhibitor 1 is an irreversible USP inhibitor with submicromolar IC50 of USP4 and its phylogenetic relative USP11, also functionally inhibits USP33, leading to CP110 instability and synergy with ATR inhibition in U2OS cells.
| M.Wt | 290.747 | |
| Formula | C15H15ClN2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ward JA, et al. ACS Chem Biol. 2016 Dec 16;11(12):3268-3272.
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