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Chemical Structure : C598-0556
Catalog No.: PC-38771Not For Human Use, Lab Use Only.
C598-0556 is a selective, small molecule inhibitor of USP10, inhibits USP10 comparably to HBX19818 (IC50=10 uM), with no inhibition against USP7 (IC50>100 uM).
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C598-0556 is a selective, small molecule inhibitor of USP10, inhibits USP10 comparably to HBX19818 (IC50=10 uM), with no inhibition against USP7 (IC50>100 uM).
Small molecule inhibition of USP10 leads to degradation of SYK and targeted killing of activated SYK-driven cells.
C598-0556 induces degradation of SYK in AML cells.
| M.Wt | 481.012 | |
| Formula | C27H30ClFN4O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Jing Yang, et al. Br J Cancer. 2020 Apr 14; 122(8): 1175–1184.
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