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USP7-IN-1

Chemical Structure : USP7-IN-1

CAS No.: 1381291-36-6

USP7-IN-1

Catalog No.: PC-45056Not For Human Use, Lab Use Only.

USP7-IN-1 is a novel selective and reversible inhibitor of USP7 with IC50 of 33 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

USP7-IN-1 is a novel selective and reversible inhibitor of USP7 with IC50 of 33 uM.
USP7-IN-1 shows less or no inhibition on USP5, USP8, Uch-L1, Uch-L3 and Caspase (IC50>200 uM).
USP7-IN-1 inhibits HCT116 cell viability with GI50 of 67 uM.

Physicochemical Properties

M.Wt 425.908
Formula C23H24ClN3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 40 mg/mL

Chemical Name/SMILES

4(3H)-Quinazolinone, 7-chloro-3-[[4-hydroxy-1-(1-oxo-3-phenylpropyl)-4-piperidinyl]methyl]-

References

1. Patent. WO 2013030218 A1 20130307.

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